ORGANISATION/COMPANYRIKEN(The Institute of Physical and Chemical Research)
RESEARCH FIELDComputer scienceEngineering › Computer engineeringEngineering › Knowledge engineeringInformation science › Library scienceNeurosciencesTechnology › Computer technologyTechnology › Information technology
RESEARCHER PROFILERecognised Researcher (R2)
APPLICATION DEADLINE06/11/2019 23:59 - Asia/Tokyo
LOCATIONJapan › Hyogo
TYPE OF CONTRACTTemporary
HOURS PER WEEKSee description
Laboratory for Brain Connectomics Imaging
RIKEN Center for Biosystems Dynamics Research
(Team Leader: Takuya Hayashi)
The Center for Biosystems Dynamics Research (BDR) views the functions of molecules, cells, and organs that support all life stages of organisms as a dynamic system, and aims to elucidate developmental, growth and aging phenomena as well as apply their findings to develop regenerative medicine and diagnostics, thereby contributing to the extension of healthy life expectancies.
The Hayashi laboratory focuses on comparative neuroscience in the emerging field of primate brain connectomics using magnetic resonance imaging. We are continuing to refine non-invasive brain connectomics imaging technologies, including data acquisition (3D coil design, sequence development), preprocessing (motion & homogeneity correction, registration, parcellation, cortical surface reconstruction), computational modeling & hardware design, and databasing and sharing. We collect large amounts of in vivo data from humans and non-human primates (NHP), standardizing data into a common space by applying mathematical image processing grounded in neuroanatomical and functional correspondences. We use a 3T MRI scanner (Siemens MAGNETOME Prisma) installed in our center to achieve these goals.
We seek to understand the genesis of human behavior by associating brain connectivity, genetics and environment. We address questions how primate brains evolved by quantifying cortical expansion, and spatio-temporal dynamics of functional and structural connectomes. We also seek to find the mechanism of dynamics and plasticity of the connectome in relation to learning of behavior and neuropsychiatric diseases such as Parkinson's disease, stroke and depression. Our lab collaborates closely with David Van Essen and Matthew Glasser at Washington University in St. Louis, core members of Human Connectome Project (HCP) in USA. We also collaborate with Stephen Smith (Oxford University, Oxford), Gary Hui Zhang (University College of London, London), Henry Kennedy (Stem Cell Brain Research Institute, Lyon), Alain Dagher (MNI, McGill University, Montreal), Jun Takahashi (CiRA, Kyoto University, Kyoto), Takashi Hanakawa (NCNP, Tokyo), Norihiro Sadato (NIPS, Okazaki), Mitsuo Kawato (ATR, Nara), Tetsuo Yamamori (RIKEN CBS, Wako) and others. We also collaborate with multiple R&D companies on the development of medical imaging devices, diagnostic technologies, and therapeutics. Our lab is funded by national research grants, Brain/Mind and Brain/Mind-beyond from AMED and KAKENHI from MEXT and JSPS. Lab members are encouraged to communicate and present their work in English, and to exchange research topics and technologies with others outside lab. Lab alumni currently work at major universities and research institutes.
For more information, please refer to above "Job posting URL(Laboratory for Brain Connectomics Imaging website)" and our recent publication on the cortical neurite distributions revealed by MRI.
[Job title and Job description]
enior Scientist or Research Scientist, 1 person
The successful candidate will investigate the organization, dynamics and evolution of brain connectivity in primates (humans, macaques and marmosets). He or she will analyze data of brain connectomics imaging using multi-modal and multidisciplinary approaches including neuroimage preprocessing, computational modeling, and neuroinformatics. This will entail using scripting languages for analyzing data, and writing scientific manuscripts that reveal details or dynamics of brain connectomics by comparing species and associating with behaviors, genes etc. Analysis of brain imaging data will include human and non-human primate versions of the HCP's minimal preprocessing pipeline (MPP), Connectome Workbench, FSL, Freesurfer, Matlab. Statistical analysis will be done with Matlab, and R. Machine learning and deep learning techniques may be used for improving analysis. Brain connectomics data we use are HCP-Style high-quality, high-resolution structural MRI (T1w, T2w), resting-state and task functional MRI, and diffusion MRI, as well as lower quality or legacy data, obtained in our lab or others. The senior scientist is expected to assist the leader of their team, provide instruction to researchers or other members and carry out the research in the team. The research scientist is expected to focus on carrying out research and other work in accordance with research themes of the team.
The lab is located in RIKEN Kobe campus in Kobe, Japan. The city of Kobe is located in the Western part of Japan in a unique setting between the Rokko Mountains and the Inland Sea. The city's port has historically played an important role in opening Japan up to international influence and the city retains a cosmopolitan and sophisticated air to this day. In addition to a bustling Chinatown and the more relaxed historical foreign settlement, there are a number of international restaurants, jazz bars, and hot springs. Japan's renowned public transport system also means that Kobe is within easy reach of the ancient capitals of Kyoto and Nara, which contain over 1,000 historical temples and shrines.
Laboratory for Brain Connectomics Imaging.
RIKEN Center for Biosystems Dynamics Research
6-7-3 Minatojima-minamiamachi, Chuo-ku, Kobe 650-0047, Japan
[Start of Employment]
For details about "Salary and benefits", please refer to above "Job posting URL".
Handling Personal Data:
Handling of Personal Data: All private data sent to RIKEN in application for employment is handled in strict confidentiality, and such data is not utilized for any other purpose or disclosed to any third party. Application documents will not be returned.
Updated as of Apr 3, 2019: "Required documents"
Updated as of Sep 9, 2019: "Available Positions"
EURAXESS offer ID: 353512
Posting organisation offer ID: D118110258
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