ORGANISATION/COMPANYRIKEN(The Institute of Physical and Chemical Research)
RESEARCHER PROFILERecognised Researcher (R2)
APPLICATION DEADLINE17/07/2020 23:59 - Asia/Tokyo
LOCATIONJapan › Saitama
TYPE OF CONTRACTTemporary
HOURS PER WEEKSee description
Laboratory for Circuit and Behavioral Physiology, Center for Brain Science (Team leader:Thomas Mchugh)
We have recently combined our expertise in physiology with the emerging technology of memory engram labeling, based on the combination of immediate early gene expression and optogenetics, to functionally tag, identify & manipulate neurons involved in the encoding of a specific memory. Building on this we will collect and analyze high-density recording of neuronal activity in the other regions of the hippocampus and cortex, allowing us to examine the interactions of neurons across brain regions during memory consolidation and recall. Further, the identification of a general signature of neurons engaged by memory will allow us to train algorithms with data from the high density recording to permit the identification of engram neurons based on physiology alone, without the need for optogenetic identification. These efforts will allow us to create models to classify memory age and quality based on physiology and better understand how temporal and spatial organization of activity can improve memory and brain health in cases of disease.
[Job title and description]
Job title, available positions:
Research Scientist (1)
The candidate will take the lead in generating analytical and computational approaches to capture key features of electrophysiological data recorded in mouse hippocampus and cortex. This work will be done in close collaboration with experimentalists conducting high density neural recordings combined with optogenetic methods to jointly design new paradigms based on observations and predictions spurring from the theoretical work.
Branch and address:
RIKEN Wako (2-1 Hirosawa, Wako, Saitama 351-0198)
[Start of employment]
As early as possible
For details about "Salary and benefits", please refer to the above "Job posting URL".
Handling personal data:
EURAXESS offer ID: 433793
Posting organisation offer ID: D119071202
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