ORGANISATION/COMPANYDWI - Leibniz Institute for Interactive Materials
RESEARCH FIELDChemistry › BiochemistryChemistry › Physical chemistryEngineering › Microengineering
RESEARCHER PROFILERecognised Researcher (R2)
APPLICATION DEADLINE04/03/2020 22:00 - Europe/Athens
LOCATIONGermany › Aachen
TYPE OF CONTRACTTemporary
HOURS PER WEEK40
EU RESEARCH FRAMEWORK PROGRAMMEH2020 / ERC
We are looking for a passionate and talented postdoc with a keen interest in constructing artificial cells bottom-up with microfluidics. You should have excellent communication skills and be able to operate in a dynamic international research team.
The high concentration of molecules inside the cell makes it a highly thermodynamically nonideal environment. This nonideal environment prevents understanding protein behavior from first principles. Moreover, the nonideal conditions prevent an understanding of the overall biochemical organization in cells and their physical properties. In this project, you aim to reconstruct the biochemical organization found in living cells. You will fabricate these artificial systems by microfluidics to achieve a rapid and reliable output. The lab devised new methods to probe the biochemical organization with optical techniques that allow rapid screening. Together, this will provide an excellent platform to demystify what governs biochemical organization, and will provide a robust platform for exciting novel applications in the clinical arena.
This research is funded by an ERC consolidator grant and will be executed in the Boersma group at the DWI-Leibniz Institute for Interactive Materials in Aachen. The institute has excellent infrastructure for microfluidics, which is a major research focus of the institute. Further, the institute has close connections with the nearby University Medical Center and constructs a novel “first in translation” building in the next years, which eases the development of medical devices. The institute has a strong collaborative mentality. The Boersma group builds synthetic systems from biological parts for materials with advanced functions, including intracellular sensors and biomedical diagnostic tools. The lab has been especially successful in recent years on FRET sensor development with the first sensors for the macromolecular crowding (Nature Methods 2015) and ionic strength (ACS Chem Biol 2017). The group operates on the interface of biophysics, synthetic biochemistry, and organic chemistry.
Further information on the group and institute can be found at:
You hold a Ph.D. in biophysics, physical chemistry, chemical engineering, or related field. Your previous Ph.D. or postdoc research had a significant microfluidics component. You have an affinity with biomolecules and biomolecular systems. In addition, you are creative, proactive, and able to work in a multidisciplinary research team. Further, you have a good knowledge of the English language (spoken and written).
Interested? This vacancy is open until 8 March 2020. Please send your application including CV, contact details of two references, and motivation letter in a single pdf to:
Dr. Arnold J. Boersma
EURAXESS offer ID: 488559
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